Here's a list of main characters or recurring characters that have died:
7.Denny Duquette Jr.
11 people who are main or recurring characters died. Now I know that some people have to die in order to keep the show interesting, but it's really upsetting especially when you grow close to the characters (*cough* Mark and Lexie *cough*.) Also do you even know of a hospital where so many doctors/residents/interns die? It's also an unrealistic way for a bunch of doctors to die especially in one hospital.
- Lexie and Mark: Plane Crash.
- George O'Malley: Dragged by a bus.
- Heather Brooks: Electrocuted and head hit on a generator.
- Reed Adamson and Charles Percy: Shot by a gunman.